Oct 30 – Nov 1, 2026 MIT Media Lab

ScienceClaw A hackathon for building decentralized collectives of AI agents that solve real scientific and technical problems.

Final application deadline: October 26, 2026

3 daysIn-person
2–5Per team
∞Agent collectives
4Challenge Areas
01

Overview

Purpose

ScienceClaw explores when decentralized collective intelligence can produce capabilities beyond a single agent or conventional workflow.

Teams build working collectives of specialized agents, models, simulations, sensors, and laboratory tools. Different members of the collective can hold distinct knowledge and capabilities, coordinate and adapt, and leave traceable scientific artifacts, provenance, findings, and unmet needs that the collective can build upon—without requiring one central planner to prescribe the entire process.

Challenge

Teams identify a difficult scientific or technical problem and build a functioning agentic system to address it. Each project should demonstrate:

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Problem

Identify a difficult, open-ended, consequential scientific or technical challenge.

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Functioning System

Build a working agentic system — not just a concept or architecture.

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Result

Demonstrate what the system actually accomplishes.

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Validation

Provide convincing evidence, benchmarks, or real-world validation.

The goal is not simply to propose an idea or agent architecture, but to demonstrate a working system and what it can accomplish.

02

Build

Resources & Technology

ScienceClaw is model- and framework-agnostic. Teams can combine frontier models, open models, their own models, existing agent frameworks, scientific datasets, compute, sensors, and laboratory infrastructure.

We will provide access to a shared pool of resources, including compute, models, tools, and other infrastructure, where available. Resources are limited and will be allocated based on project needs, technical fit, and availability.

R1

AI models & tools

Foundation models, agent frameworks, and open tooling to compose into collectives.

R2

Compute & tokens

Shared compute and model resources may be available for project work, subject to project needs, technical fit, and availability.

R3

Hardware

Microcontrollers, sensors, and instruments for agents that act in the world.

R4

Open problem space

Sponsor-led challenges provide concrete inspiration — unexpected approaches welcome.

The goal is not to prove that one model is best. Teams can use, reuse, modify, and combine available technology—including capabilities developed during the event—to build a functioning decentralized system that accomplishes something scientifically meaningful.

Challenge Areas

Scientific domains are intentionally open. We provide challenge seeds, problems, datasets, resources, or sponsor-led challenges to provide entry points without constraining what teams build.

A·01

Biology & Protein Design

Collectives that hypothesize, design, and iterate across sequence, structure, and function.

A·02

Physical Agency

Agents that reach beyond the browser into sensors, instruments, and cloud laboratories.

A·03

Manufacturing & Materials

From candidate discovery to fabrication — closing the loop between simulation and matter.

A·04

Open Scientific Challenge

Participant-defined problems. Bring the question you can't stop thinking about.

Teams can formulate their own problems and work across challenge areas. There is one overall competition, rather than separate tracks.

The Hackathon as a Multi-Agent System

The hackathon operates across multiple levels:

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Agents

Collaborate within teams to solve problems.

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Teams

Exchange capabilities across teams.

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Ecosystem

Successful capabilities propagate because they increase the effectiveness of other systems.

The competition therefore becomes a live experiment in decentralized collective intelligence: teams compete to build strong systems while also having an incentive to make the broader ecosystem stronger.

03

Competition

Judging

Science is the benchmark. Success is not simply whether an agent completed a task, but whether the system produced a scientifically meaningful result supported by evidence, validation, or measurable progress.

The judging rubric also asks whether organizing capabilities as a decentralized collective adds something beyond a single agent, isolated agents, or a conventional workflow.

Problem Significance & Complexity

How difficult, open-ended, consequential, and scientifically meaningful is the problem? Does solving it meaningfully advance a scientific or technical goal?

20%

Scientific/Technical Impact

What was actually achieved? Is the result novel, meaningful, rigorous, and potentially useful?

25%

Decentralized Agency

Are decision-making and capabilities meaningfully distributed across agents? Do agents have distinct information, resources, or capabilities? Can they coordinate and adapt without a central planner prescribing the entire trajectory?

20%

Collective Capability

Does organizing agents collectively add measurable capability? Where possible, demonstrate this through a simple comparison such as multi-agent vs. single-agent, collaborative vs. isolated, or decentralized vs. centralized.

25%

Execution and Validation

Is there a functioning system rather than just a concept? Is its performance demonstrated with convincing evidence, benchmarks, or real-world validation?

10%

Collaboration Bonus: +10 — Collaboration is not part of the core judging score. Teams can earn up to +10 points by creating capabilities that materially strengthen other teams, such as:

  • A tool or agent successfully reused by another team
  • Data, discoveries, or experiments that enable another team's result
  • Infrastructure that improves multiple systems
  • Capabilities that propagate through the ecosystem

Judges

Avijit Ghosh

Lead Technical AI Policy Researcher at Hugging Face

Desiree Plata

Associate Dean of Engineering at MIT

Yilun Du

Assistant Professor at Harvard

Riken Shah

Human Data team at xAI

Ian Ferguson

Director of Hardware at FormLabs

Nikita Fedik

Senior Technical Marketing Engineer at NVIDIA

Prizes

E14 Fund Prize

$50K*

* Founder-friendly investment: $50K SAFE (no cap, no discount) on incorporation of an E14-backable startup.

04

Schedule

Friday

  1. Registration begins
  2. Dinner
    presented by MIT School of Engineering
    Location: Winter Garden
  3. Welcome and IntroductionsLocation: Main Stage
  4. NVIDIA: Agentic Methods for ALCHEMI and BioNeMoLocation: Main Stage
  5. Platform and Challenge PresentationsLocation: Main Stage
  6. Team FormingLocation: Main Stage

Saturday

  1. Breakfast
    presented by Romix Biosciences
    Location: Winter Garden
  2. Formlabs Preform API DemoLocation: Silverman Skyline
  3. Lunch
    presented by Stifel Venture Banking
    Location: Winter Garden
  4. Mentor Sessions with Reactorfield
  5. Dinner
    presented by Formlabs
    Location: Winter Garden

Sunday

  1. Breakfast
    presented by Edison Scientific
    Location: Winter Garden
  2. End of hacking - final slides due
  3. Lunch
    presented by Lila Sciences
    Location: Winter Garden
  4. Presentations & JudgingLocation: Main Stage
  5. Awards & Closing CeremonyLocation: Main Stage
05

Community

Organizing Team

Markus J. Buehler

McAfee Professor of Engineering · Director and PI, Laboratory for Atomistic and Molecular Mechanics (LAMM) · MIT

Awu Chen

M.S. Candidate, Tangible Media Group · MIT

With People From

06

FAQ

Can I participate remotely?

We won’t be set up for remote or hybrid participation. This is an in-person event.

How many people are on each team?

Teams can have 2 to 5 members, and every member should attend in person.

How do I join a team or find teammates?

If you don’t have a team yet, we’ll set aside time for team formation during kickoff on Friday, October 30. To join a team that’s already registered, apply on Luma and list your teammates’ names in your application. Once you’re approved, we’ll add you to the ScienceClaw Discord, where you can meet other participants and start forming a team before the event.

Can I volunteer?

Yes. To volunteer, email [email protected].

When and where is ScienceClaw?

ScienceClaw runs October 30–November 1, 2026 at the MIT Media Lab.

Where can I stay near MIT?

Nearby options listed by MIT include The Kendall Hotel, Boston Marriott Cambridge, and Residence Inn Boston Cambridge, all in Kendall Square. See MIT's full hotel list. MIT recommends reserving ahead and notes that it does not guarantee listed accommodations.

Can our team define its own challenge?

Yes. Teams can formulate their own scientific or technical problems and work across challenge areas. There is one overall competition, not separate tracks.

What should we build?

Build a functioning decentralized system that uses agents to make measurable progress on a meaningful scientific or technical problem. Show the result with evidence, validation, or benchmarks.

Which models and tools can we use?

ScienceClaw is model- and framework-agnostic. Use frontier or open models, your own models, agent frameworks, datasets, compute, sensors, and laboratory infrastructure.

What resources will be available?

A shared pool of compute, models, tools, and other infrastructure may be available. Resources are limited and allocated based on project needs, technical fit, and availability.

How will projects be judged?

Judges look for scientifically meaningful results, technical impact, decentralized agency, collective capability, and strong execution and validation. Teams can also earn up to 10 collaboration-bonus points for capabilities that materially help other teams.

What are the prizes?

Prizes include the E14 Fund Prize ($50K SAFE, no cap, no discount, on incorporation of an E14-backable startup), a Formlabs Form Studio 1 printer, three NVIDIA DGX Sparks, and alphaXiv OpenResearch GPU credits, with more to be announced.

How do I register?

Register through the ScienceClaw event page on Luma.

ScienceClaw · Oct 30 – Nov 1, 2026 · MIT Media Lab

Join the collective.

October 30 – November 1, 2026. Bring a problem — or come find one.

Final application deadline: October 26, 2026.

Apply now